Fernando Gombos Selected Research

Acantholysis

2/2009	High-dose pemphigus antibodies against linear epitopes of desmoglein 3 (Dsg3) can induce acantholysis and depletion of Dsg3 from keratinocytes.
3/2008	Evidence of key role of Cdk2 overexpression in pemphigus vulgaris.
1/2008	The specific proteolysis hypothesis of pemphigus: does the song remain the same?
9/2007	If pemphigus vulgaris IgG are the cause of acantholysis, new IgG-independent mechanisms are the concause.
7/2007	Defining the involvement of proteinases in pemphigus vulgaris: evidence of matrix metalloproteinase-9 overexpression in experimental models of disease.
6/2007	A novel method to investigate pemphigus-induced keratinocyte dysmorphisms through living cell immunofluorescence microscopy.
4/2007	Searching for experimental models of Pemphigus vulgaris.
2/2007	Changes in desmoglein 1 expression and subcellular localization in cultured keratinocytes subjected to anti-desmoglein 1 pemphigus autoimmunity.
6/2006	How does acantholysis occur in pemphigus vulgaris: a critical review.
5/2006	Serum from pemphigus vulgaris reduces desmoglein 3 half-life and perturbs its de novo assembly to desmosomal sites in cultured keratinocytes.

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Fernando Gombos Research Topics

Disease

10	Acantholysis 02/2009 - 05/2006
10	Pemphigus (Pemphigus Vulgaris) 02/2009 - 05/2006
3	Blister (Bulla) 03/2008 - 04/2007
3	Aphthous Stomatitis (Aphthous Ulcer) 08/2007 - 05/2003
3	Pain (Aches) 08/2007 - 04/2003
3	Cleft Lip (Harelip) 03/2006 - 06/2004
2	Cleft Palate (Palate, Cleft) 04/2005 - 01/2005
1	Hypothyroidism 01/2008
1	Atherosclerotic Plaque (Atheroma) 07/2006
1	Rupture 07/2006
1	Burning Mouth Syndrome (Syndrome, Burning Mouth) 01/2004
1	Ulcer 04/2003
1	Lichen Planus (Lichen Ruber Planus) 04/2003
1	Oral Lichen Planus 04/2003
1	Linear IgA Bullous Dermatosis 02/2003
1	Hypertension (High Blood Pressure) 02/2003

Drug/Important Bio-Agent (IBA)

6	Desmoglein 3IBA 02/2009 - 09/2005
4	AntibodiesIBA 02/2009 - 09/2005
4	Immunoglobulin G (IgG)IBA 02/2009 - 04/2007
3	AutoantibodiesIBA 02/2009 - 05/2006
2	Peptide Hydrolases (Proteases)FDA Link 01/2008 - 07/2007
2	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2007 - 05/2003
2	AntigensIBA 07/2007 - 06/2006
2	Desmoglein 1IBA 02/2007 - 06/2006
2	Folic Acid (Vitamin M)FDA LinkGeneric 04/2005 - 01/2005
2	glucuronyl glucosamine glycan sulfate (sulodexide)IBA 05/2003 - 04/2003
1	EpitopesIBA 02/2009
1	RoscovitineIBA 03/2008
1	EnzymesIBA 01/2008
1	Matrix Metalloproteinases (MMPs)IBA 01/2008
1	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2008
1	Clobetasol (Clobetasol Propionate)FDA LinkGeneric 08/2007
1	Dexamethasone (Maxidex)FDA LinkGeneric 08/2007
1	Fluocinonide (Lidex)FDA LinkGeneric 08/2007
1	Triamcinolone (Aristocort)FDA Link 08/2007
1	A-130A (A 130)IBA 07/2007
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 07/2007
1	Keratins (Keratin)IBA 06/2007
1	CytokinesIBA 04/2007
1	Dihydrotachysterol (AT 10)IBA 07/2006
1	AutoantigensIBA 06/2006
1	Desmosomal CadherinsIBA 06/2006
1	NectinsIBA 06/2004
1	Nonsense Codon (Nonsense Mutation)IBA 06/2004
1	AcidsIBA 01/2004
1	Thioctic Acid (Lipoic Acid)IBA 01/2004
1	Prednisone (Sone)FDA LinkGeneric 05/2003
1	Therapeutic UsesIBA 05/2003
1	Heparinoids (Heparinoid)IBA 04/2003
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 04/2003
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 02/2003
1	benazepril (Briem)FDA LinkGeneric 02/2003

Therapy/Procedure

4	Therapeutics 08/2007 - 04/2003
1	Operative Surgical Procedures 03/2006